Our lab is developing new methods to efficient and recyclable heterogeneous nanoporous and nanostructured catalysts for various one step and multi-step tandem catalytic transformations. The cost of these new catalysts is relatively low because they are made from commercially available materials, are very effective in chemical transformations and can be reused numerous times. We developed methods to some of the most efficient and selective nanoporous catalyst for base catalyzed reactions such the Henry and aldol condensation reactions. This catalyst significantly improves the yield of the Henry reaction and selectively produces nitro alcohol or nitrostyrene product. The catalyst is expected to find application in pharmaceuticals such as aliskiren, which is used for the treatment of hypertension and high blood pressure.