BEGIN:VCALENDAR VERSION:2.0 PRODID:-//jEvents 2.0 for Joomla//EN CALSCALE:GREGORIAN METHOD:PUBLISH BEGIN:VEVENT UID:8dac7bc5d16782dfb54b8b6edb2405e2 CATEGORIES:Colloquium CREATED:20181017T155155 SUMMARY:Professor Gang Han, University of Massachusetts LOCATION:CCB Auditorium DESCRIPTION:
“Fro m Molecule to Mammal: Inventing Luminescent Nanoparticles for B iology”
Functional luminescent nanopar ticles are promising materials for in vitro and in vivo optical imaging and therapy due to their unique optical and chemical properties. In this talk, I will present a series of biocompatible luminescence nanoparticles. The first type of materials is upconversion nanoparticles (UCNPs). I will present new developments regarding engineering UCNPs towards optogenetic ap plications in immunotherapy as well as the most recent application in regar d to create mammalian infrared imaging vision. The second type of nan oparticles is persistent luminescence nanoparticles (PLNPs). They are biolu minescence-like and possess unprecedented in vivo deep tissue energy rechar geability, outstanding signal-to-noise-ratio with no need for an excitation resource (light) during imaging, and they can be directly detected with ex isting imaging systems. These nanoparticles continue to emit light for minu tes or hours and, in some cases, days, after turning off the excitation sou rce. These long-lasting, light-emitting nanocrystals can provide noninvasiv e imaging technology for evaluating structural and functional biological pr ocesses in living animals and patients. The third is a type of organic Biod py nanoparticles that were tailored with outstanding NIR absorbing ability. Rather than the conventional laser light needed in PDT, I will present the ir ultralow power lamp operable PDT applications in deep tissue tumor treat ment. Finally, I would like also to introduce a new organic upconversion sy stem for in vivo anticancer release.
~ Coffee/tea wi ll be served prior to lecture~
X-ALT-DESC;FMTTYPE=text/html:“From Molecule to Mammal: Inventing Luminescent&nbs p;Nanoparticles for Biology”
Fu nctional luminescent nanoparticles are promising materials for in vitro and in vivo optical imaging and therapy due to their unique optical and chemic al properties. In this talk, I will present a series of biocompatible luminescence nanoparticles. The first type of materials is upconversion na noparticles (UCNPs). I will present new developments regarding engineering UCNPs towards optogenetic applications in immunotherapy as well as the most recent application in regard to create mammalian infrared imaging vision.& nbsp; The second type of nanoparticles is persistent luminescence nanoparti cles (PLNPs). They are bioluminescence-like and possess unprecedented in vi vo deep tissue energy rechargeability, outstanding signal-to-noise-ratio wi th no need for an excitation resource (light) during imaging, and they can be directly detected with existing imaging systems. These nanoparticles con tinue to emit light for minutes or hours and, in some cases, days, after tu rning off the excitation source. These long-lasting, light-emitting nanocry stals can provide noninvasive imaging technology for evaluating structural and functional biological processes in living animals and patients. The thi rd is a type of organic Biodpy nanoparticles that were tailored with outsta nding NIR absorbing ability. Rather than the conventional laser light neede d in PDT, I will present their ultralow power lamp operable PDT application s in deep tissue tumor treatment. Finally, I would like also to introduce a new organic upconversion system for in vivo anticancer release.
< i>~ Coffee/tea will be served prior to lecture~
X-EXTRAINFO:Hosted by Professor KiBum Lee DTSTAMP:20240329T141625 DTSTART:20190423T150000 DTEND:20190423T160000 SEQUENCE:0 TRANSP:OPAQUE END:VEVENT END:VCALENDAR