BEGIN:VCALENDAR VERSION:2.0 PRODID:-//jEvents 2.0 for Joomla//EN CALSCALE:GREGORIAN METHOD:PUBLISH BEGIN:VEVENT UID:a8a224bc0e2618eac09439d86adaca5d CATEGORIES:Colloquium CREATED:20181017T154602 SUMMARY:Professor Nathaniel Szymczak DESCRIPTION:Professor Nathaniel SzymczakUniversity of MichiganHosted by Professor Mark Lipke\nTuesday Decelber 11, 2018\n11:00AM, CCB* Auditorium \n*New Chemistry and Chemical Biology Building\n"Moving Beyond the Metal: Assisted Small Mo lecule Activation"\nThe design of metal complexes and catalysts that are ca pable of selective bond activation of small molecules has been a longstandi ng target of the synthetic community. The current paradigm primarily focuse s on a single active metal site with ligands that impart steric and electro nic tunability to achieve substrate binding and activation, with limited at tention paid to the secondary interactions of appended groups. Taking inspi ration from biological systems, our group is working to develop strategies to exploit acidic and basic groups (hydrogen bond donors, Lewis acids/bases ) to promote cooperative interactions. This presentation will emphasize how Lewis acids can be used to augment metal-based reactivity, as well as to s how how incorporation of these units within a ligand scaffold can provide a ccess to unique activation processes.\n X-ALT-DESC;FMTTYPE=text/html:
Hosted by Professor Mark Lipke
Tuesday Decelber 11, 2018
11:00AM, CCB* Auditorium
*New Chemistry and Chemical Biology Bu ilding
"Moving Beyond the Metal: Assisted Small Mo lecule Activation"
The design of metal complexes and catalysts that a re capable of selective bond activation of small molecules has been a longs tanding target of the synthetic community. The current paradigm primarily f ocuses on a single active metal site with ligands that impart steric and el ectronic tunability to achieve substrate binding and activation, with limit ed attention paid to the secondary interactions of appended groups. Taking inspiration from biological systems, our group is working to develop strate gies to exploit acidic and basic groups (hydrogen bond donors, Lewis acids/ bases) to promote cooperative interactions. This presentation will emphasiz e how Lewis acids can be used to augment metal-based reactivity, as well as to show how incorporation of these units within a ligand scaffold can prov ide access to unique activation processes.
DTSTAMP:20240329T022705 DTSTART:20181211T160000 DTEND:20181211T170000 SEQUENCE:0 TRANSP:OPAQUE END:VEVENT END:VCALENDAR