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Morteza Mahmoudi, Michigan State University
Tuesday, February 09, 2021, 11:00am - 12:00pm

Morteza MahmoudiNanoBio Interfaces: Opportunities and Challenges of Protein Corona

Nanoparticles (NPs) are becoming increasingly promising tools for medical diagnostics and therapeutics. Despite the advances in their biomedical applications and numerous publications, fewer than expected NPs have made it to clinical trials and even fewer have reached clinical practice. This wide gap between bench discoveries and clinical applications is mainly because of our limited understanding of the nanobiointerfaces. Although extensive studies have been conducted to enhance our understanding of the nanobiointerfaces, the literature remains unclear and contains conflicting information, even for seemingly identical NPs. The main goal of this talk is to introduce some of the existing “overlooked” factors at the nanobiointerfaces to determine – unambiguously and reproducibly – the biological fate of NPs both in vitro and in vivo. Deeper understanding of the nanobiointerfaces, using the overlooked factors, may accelerate clinical translation of nanobiotechnologies. The talk also covers critical applications of nanobiointerfaces in cardiovascular regenerative medicine, and defines how this knowledge can substantially resolve some of the major issues in myocardial regeneration.

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Meeting ID: 969 5670 6663
Password: 477159

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Meeting ID: 969 5670 6663

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Hosted by Professor KiBum Lee