Professor Akif Tezcan
University of California, San Diego
Tuesday May 22, 2018
3:30 PM, WL 260
"Protein Self-Assembly by Chemical Design"
Proteins represent the most versatile building blocks available to living organisms or the laboratory scientist for constructing functional materials and molecular devices. Underlying this versatility is an immense structural and chemical heterogeneity that renders the programmable self-assembly of proteins a highly challenging goal. To circumvent the challenge of designing extensive non-covalent interfaces for controlling protein self-assembly, we have endeavored to use bonding strategies based on fundamental principles of inorganic and supramolecular chemistry. These strategies have resulted in discrete or periodic protein architectures that are highly ordered yet dynamic and stimuli-responsive, and possess emergent functional and physicochemical properties. In this talk, I will present some of the such protein-based materials constructed in our laboratory.