I am Dr. Nagarajan Murali, a Senior NMR Researcher at the NMR facility in the Department of Chemistry and Chemical Biology (CCB) at Rutgers.
The department house a total of 8 spectrometers in two separate buildings.
The Chemistry NMR Facility houses four spectrometers (VNMRS 500, 400, 300, and a Bruker solid-state 400) for the Chemistry department use and are located at the Wright-Rieman Chemistry Lab. I take care of the use, maintenance, and user training of these instruments.
The other four high field spectrometers for Bio-NMR research are located at the Proteomics center. These are: Bruker Avance III HD 800, Bruker Avance III 700, Bruker Avance III 600, and Bruker Avance III HD 600 MHz spectrometers. The 800 and 700 NMR systems have cryogenically cooled probes. The Avance III HD 600 system is equipped for bio solid state NMR application. The solid-state 400 NMR at CCB with its 3.2mm CHN - Efreee Bio-Solids probe is also capable of biological solids NMR applications. Dr. Seho Kim manages the bio-nmr applications and I take care of the hardware issues and act as a liaison with the vendors.
My own interests are in NMR methods development and theoretical aspects of relaxation in NMR. A graduate level course titled NMR Spectroscopy: Principles and Applications was developed and taught during spring 2010. As a facility manager, my core efforts are in helping researchers achieve their goals in NMR applications.
Research training is a major component of the undergraduate program in the Department of Chemistry and Chemical Biology and I enjoy contributing towards that by training young students in NMR. Their enthusiasm and energy are contagious and I draw my own inspiration to teach from these interactions.
- Flip angle dependence in two-dimensional multiple quantum coherence NMR spectroscopy; N. Muarli, Y.V.S. Ramakrishna, K. Chandrasekhar, M. Albert Thomas, and Anil Kumar; Pramana 23, 547-557 (1984).
- Superior pulse schemes for spin-echo correlated and other two-dimensional homonuclear correlated spectroscopies; Anil Kumar, R.V. Hosur, K. Chandrasekhar, and N. Murali; J. Magn. Reson. 63, 107-114 (1985).
- Multiple quantum artifacts in single quantum two-dimensional correlated NMR spectroscopy of strongly coupled spins; N. Murali and Anil Kumar; Chem. Phys. Lett. 128, 58-61 (1986).
- Use of 450 pulse-pair as a filter for pure phase tw0-dimensional NMR spectroscopy; N. Murali, K. Chandrasekhar, and Anil Kumar; J. Magn. Reson. 70, 153-156 (1986).
- Coherence transfer via longitudinal spin-order and generalised pulse pair filtering for pure phase two-dimensional NMR spectroscopy; N. Murali and Anil Kumar; Chem. Phys. Lett. 137, 324-329 (1987).
- A diffusion equation approach to spin diffusion in bio-molecules; V.V. Krishanan, N. Murali, and Anil Kumar; J. Magn. Reson. 84, 255-267 (1989).
- NMR dipole-dipole refocusing with shaped pulses; C.J. Lee, N. Murali, W.S. Warren; J. Magn. Reson. 84, 643-647 (1989).
- Application of shaped pulses to high resolution NMR in dipolar broadened systems; C.J. Lee, N. Murali, W.S. Warren; Advances in Magn. Reson. 14, 241-268 (1990).
- Two-dimensional nuclear Overhauser effect spectroscopy (TRNOESY) studies of nucleotide conformation in creatine kinase complexes: Effects of non-specific binding; N. Murali, G.K. Jarori, S.B. Landy, and B.D. Nageswara Rao; Biochemistry 32, 12941-12948 (1993).
- Two-dimensional transferred nuclear Overhauser effect spectroscopy (TRNOESY) studies of the conformation of MGATP bound at the active and ancillary sites of rabbit muscle pyruvate kinase; G.K. Jarori, N. Murali, and B.D. Nageswara Rao; Biochemistry 33, 6784-6791 (1994).
- Two-dimensional transferred nuclear Overhauser effect spectroscopy (TRNOESY) studies of nucleotide conformations in arginine kinase complexes; N. Murali, G.K. Jarori, and B.D. Nageswara Rao; Biochemistry 33, 14227-14236 (1994).
- Conformation of MgATP bound to phosphoribosylpyrophosphate synthetase by two-dimensional transferred nuclear Overhauser spectroscopy (TRNOESY); G.K. Jarori, Nagarajan Murali, R.L. Switzer, and B.D. Nageswara Rao; Eur. J. Biochemistry 230, 517-524 (1995).
- Lineshape variations of a spin-1/2 nucleus coupled a quadrupolar spin subjected to RF irradiation: Selective suppression of relaxation pathways by decoupling; N. Murali and B.D. Nageswara Rao; J. Magn. Reson. Ser.A 118, 202-213 (1996).
- Conversion of DNA binding proteins into DNA binding drugs: Structural redesign of the overlapping b-turns of RNA polymerase II; J.R. Dobbins, N. Murali, and E.C. Long; Int. J. Peptide & Protein Res. 47, 260-268 (1996).
- Adenosine conformation in nucleotides bound to methionyl tRNA synthetase by TRNOESY; Nagarajan Murali, Y.Lin, Y. Mechulam, P. Plateau, and B.D. Nageswra Rao; Biophysical J. 72, 2275-2284 (1997).
- Relaxation effects in system of spin-1/2 nucleus coupled a quadrupolar spin subjected to RF irradiation: Evaluation of broadband decoupling schemes; S.A. Smith and Nagarajan Murali; J. Magn. Reson. 136, 27-36 (1999).
- Application of a high resolution superconducting NMR probe in natural product structural determination; T.M. Logan, Nagarajan Murali, G. Wang, and C. Jolivet; Magn. Reson. Chem. 37, 512-515 (1999).
- High resolution liquid-state NMR above one gigahertz; Y.-Y. Lin, S. Ahn, N. Murali, W. Brey, C.R. Bowers, and W.S. Warren; Phys. Rev. Lett. 85, 3732-3735 (2000).
- A Primer for Nuclear Magnetic Relaxation in Liquids; Nagarajan Murali and V.V. Krishnan; Concepts in Magn. Res. Part A Vol. 17A, 86-116 (2003).
- Pulse schemes for detection of quaternary carbons with and without proton decoupling; G.A.N Gowda, Nagarajan Murali, B.S. Joshi, R. Roy, and C.L. Khetrapal; Journal of The Indian Chemical Society. 80(4), 367-371, 2003.
- NMR Analyses of the Activation of the ARP2/3 Complex by Neuronal Wiskott-Aldrich Syndrome Protein; M.K. Deitrick, E.D. Goley, C. Denison, C. Egile, R. Li, Nagarajan Murali, T.J. Kodadek, M.D. Welch, and M.K. Rosen; Biochemistry 44, 15247-15256, 2005.
- Spectral Unravelling by Space-selective Hadamard Spectroscopy; Nagarajan Murali, W.M. Miller, B.K. John, D. Avizonis, and S.H. Smallcombe; J. Magn. Reson. 179, 176-183, 2006.
- IDEAL-A Fast Single Scan Method for X-Pulse Width Calibration; Nagarajan Murali; J. Magn. Reson. 183, 142-144, 2006.
- Radiation damping in modern NMR experiments: Progress and challenges; V. V. Krishnan and Nagarajan Murali; Progress in NMR Spectroscopy 68, 41-57, 2013.
- Efficient Tertiary Amine/Weak Acid Bifunctional Mesoporous Silica Catalysts for Michael Addition Reactions; Sayantani Das, Anandarup Goswami, Nagarajan Murali, and Tewodros Asefa; ChemCatChem 5(4), 910-919, 2013.
- Biological control of aragonite formation in stony corals; Stanislas Von Euw, Qihong Zhang, Viacheslav Manichev, Nagarajan Murali, Juliane Gross, Leonard C. Feldman, Torgny Gustafsson, Carol Flach, Richard Mendalsohn, Paul G. Falkowski; Science 356, 933-938, 2017.
- Selective CO2 reduction to C3 and C4 oxyhydrocarbons on nickel phosphides at overpotentials as low as 10mV; Karin U.D. Calvinho, Anders B. Laursen, Kyra M.K. Yap, Timothy A. Goetjen, Shinjae Hwang, Nagarajan Murali, Bryan Mejia-Sosa, Alexander Lubarski, Krishani M. Teeluck, Eugene S. Hall, Eric Garfunkel, Martha Greenblat, and Charles Dismukes; Energy & Environmental Sciences 11, 2550-2559, 2018
Department of Chemistry and Chemical Biology
Rutgers, The State University of New Jersey
610 Taylor Road
Piscataway, NJ 08854
Chemistry department stockroom staffed during business hours (8:30AM-3:30PM)