Poly(anhydride-esters) Comprised Exclusively of Naturally-occurring Antimicrobials and EDTA: Antioxidant and Antibacterial Activities

Naturally derived antioxidants and antimicrobials (eugenol, carvacrol, thymol) were chemically incorporated as pendant groups into biodegradable poly(anhydride-esters) composed of ethylenediaminetetraacetic acid as backbone, and hydrolytic degradation of these polymers yielded the free compounds which exhibited bioactivity.

Publication: 

Carbone-Howell, AL; Stebbins, N; Uhrich, KE “Poly(anhydride-esters) Comprised Exclusively of Naturally-occurring Antimicrobials and EDTA: Antioxidant and Antibacterial Activities”, Biomacromolecules, 15 (5) 1889–1895 (2014).   10.1021/bm500303a

Group Members: 

Stephan Bien-Aime and Nicholas D. Stebbins

Year of Research Highlight: 
2014