CHEMISTRY AND CHEMICAL BIOLOGY
SPRING 2013 COLLOQUIUM
Tuesday, February 5, 2013
Texas A&M University
"Tuning the Structure and Function of Metal-Organic Frameworks through
In an assembly procedure of a metal-organic framework (MOF), the metal (or metal-containing) node is either predetermined by the metal coordination-preference or dominated by assembly conditions that determine cluster formation. This often happens in situ and is difficult to control, although once the right conditions are found, the MOF can be reproduced consistently. On the other hand, a ligand is often synthesized pre-assembly and remain intact during and after assembly except in the rare case of an in situ ligand formation. Tuning the structure and function of a MOF through changing of metal-containing node is not as convenient as doing so via ligand design. For instance, coordination of metal nodes by bridging organic linkers leads to a metal-organic polygon or polyhedron (MOP) with a convergent ligand(s) or a metal-organic framework (MOF) with a divergent one(s). Ligands can also be extended, truncated, functionalized, or fragmented giving rise to a variety of MOFs. The inherent porosity of these MOFs can be utilized to store or capture various gases including hydrogen, methane, and carbon dioxide. In addition, ultra-stable MOFs functionalized with iron-porphyrins containing large open channels can oxidize peroxidase substrates.
~Coffee/tea will be served prior to lecture~