Bioorganic and organic reactivity is examined using analytical methods, including computational chemistry and mass spectrometry. Specific projects include the study of damaged DNA, carbene reactivity, and catalysis.
GPA: > 3.5
Course Experience: Ideally both semesters of organic though particularly strong students have started as early as freshman year
Current Undergraduate Researchers
- Aaron Petronico
- Jimmy Patel
- Julianne Davis
Publications with Undergraduate Co-authors
Michelson, A. Z.; Petronico, A. "2-Pyridone and Derivatives: Gas Phase Acidity, Proton Affinity, Tautomer Preference and Leaving Group Ability," J. Org. Chem., 2012, 77, 1623-1631.
Rozenberg, A; Lee, J. K. "Theoretical Studies of the Quinolinic Acid to Nicotinic Acid Mononucleotide Transformation," J. Org. Chem., 2008, 73, 9314-9319.
Pan, S.; Verhoeven, K.; Lee, J. K. "Investigation of the Initial Fragmentation of Oligodeoxynucleotides in a Quadrupole Ion Trap: Charge Level-Related Base Loss," J. Am. Soc. Mass Spectrom. 2005, 16, 1853-1865.
Schulze, S. M.; Santella, N.; Grabowski, J. J., Lee, J. K. "The Anionic Oxy-Cope Rearrangement: Using Chemical Reactivity to Reveal the Facile Isomerization of the Parent Substrates in the Gas Phase," J. Org. Chem. 2001, 66, 7247-7253.